{"id":408,"date":"2017-07-24T09:28:37","date_gmt":"2017-07-24T13:28:37","guid":{"rendered":"https:\/\/elearning.wfh.org\/resource\/outil-devaluation-des-saignements-de-listh\/"},"modified":"2022-09-21T15:27:26","modified_gmt":"2022-09-21T19:27:26","slug":"outil-devaluation-des-saignements-de-listh","status":"publish","type":"resource","link":"https:\/\/elearning.wfh.org\/fr\/resource\/outil-devaluation-des-saignements-de-listh\/","title":{"rendered":"Outil d\u2019\u00e9valuation des saignements de l\u2019ISTH"},"content":{"rendered":"<h3>International Society on Thrombosis and Haemostasis\/Scientific and Standardization Committee Bleeding Assessment Tool (ISTH BAT)<\/h3>\n<p class=\"\"><strong>Authors\/developers<\/strong><br class=\"\" \/>Rodeghiero F, Tosetto A, Abshire T, Arnold DM, Coller B, James P, Neunert C, Lillicrap D on behalf of the ISTH\/SSC Joint VWF and Perinatal\/Pediatric Haemostasis Subcommittees Working Group<\/p>\n<p class=\"\"><a href=\"https:\/\/www1.wfh.org\/docs\/en\/Resources\/Assessment_Tools_ISTHBAT.pdf\" target=\"blank\" rel=\"noopener\">Questionnaire and scoring sheet<\/a><\/p>\n<h6><em>N.B.: These scores are posted with the permission of the developers.<\/em><\/h6>\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"7958\" class=\"elementor elementor-7958\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-10245cc2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"10245cc2\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6adf38f7\" data-id=\"6adf38f7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1749d7e1 elementor-widget elementor-widget-spacer\" data-id=\"1749d7e1\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-34e1eec9 elementor-widget elementor-widget-html\" data-id=\"34e1eec9\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\r\n\r\n\/* Style the tab *\/\r\n.popTab {\r\n  float: left;\r\n  border: 1px solid #ccc;\r\n  background-color: #f1f1f1;\r\n  width: 35%;\r\n  height: 500px;\r\n}\r\n\r\n\/* Style the buttons inside the tab *\/\r\n.popTab button {\r\n  display: block;\r\n  background-color: inherit;\r\n  color: black;\r\n  padding: 15px 10px;\r\n  width: 100%;\r\n  border: none;\r\n  border-radius: 0;\r\n  outline: none;\r\n  text-align: left;\r\n  cursor: pointer;\r\n  transition: 0.3s;\r\n  font-size: 1.3em;\r\n}\r\n\r\n\/* Change background color of buttons on hover *\/\r\n.popTab button:hover {\r\n  background-color: #ddd;\r\n}\r\n\r\n\/* Create an active\/current tablink class *\/\r\n.popTab button.active {\r\n  background-color: #ccc;\r\n  border: none!important;\r\n}\r\n\r\n\/* Style the tab content *\/\r\n.popContent {\r\n  float: left;\r\n  padding: 0px 1em;\r\n  border: 1px solid #ccc;\r\n  width: 65%;\r\n  border-left: none;\r\n  height: 500px;\r\n  overflow-y:auto;\r\n}\r\n\r\n.popContent table tr {\r\n    \/*pointer-events: none;*\/\r\n\r\n}\r\n\r\n.popContent table td {\r\n    border-top: none;\r\n    border-left: none;\r\n    border-right: none;\r\n    border-bottom: 1px solid #eee;\r\n    background-color: white!important;\r\n    padding-left: 0;\r\n}\r\n\r\n<\/style>\r\n\r\n\r\n<div class=\"popTab\">\r\n   <button class=\"popLinks active\" onclick=\"openTab(event, 'description')\">Description<\/button>    \r\n   <button class=\"popLinks\" onclick=\"openTab(event, 'utility')\">Utility<\/button>\r\n   <button class=\"popLinks\" onclick=\"openTab(event, 'administration')\">Administration<\/button>\r\n   <button class=\"popLinks\" onclick=\"openTab(event, 'psychometrics')\">Psychometrics<\/button>\r\n   <button class=\"popLinks\" onclick=\"openTab(event, 'references')\">References<\/button>\r\n \r\n  \r\n<\/div>\r\n\r\n<div id=\"description\" class=\"popContent\">\r\n  <h3>Description<\/h3>\r\n  <p>The ISTH BAT is intended to be used in children and adults to diagnose mild bleeding disorders. The target population is patients who are being evaluated for a bleeding disorder for the first time.<sup>1<\/sup><\/p>\r\n\r\n\r\n  <p><strong>Contact person:<\/strong><br>\r\n  F Rodeghiero:\r\n<a href=\"mailto:rodeghiero@hemato.ven.it\">rodeghiero@hemato.ven.it<\/a><br>\r\nISTH-BAT Standing Committee:<br>\r\n<a href=\"http:\/\/www.isth.org\/members\/group.aspx?id=100549\" target=\"blank\" rel=\"noopener\">http:\/\/www.isth.org\/members\/group.aspx?id=100549<\/a>\r\n<\/p>\r\n\r\n<p class=\"\"><strong>Date of this review: <\/strong>August 20, 2013<br>\r\n<strong>Updated: <\/strong>April 2014<\/p>\r\n\r\n\r\n<\/div>\r\n\r\n\r\n<div id=\"utility\" class=\"popContent\" style=\"display:none\">\r\n  <h3>Utility<\/h3>\r\n  \r\n  <p><strong>Overall utility:<\/strong><\/p>\r\n  <p>Useful in the clinical setting of ruling out VWD in adults and children, or assessing for possible platelet dysfunction.<\/p>\r\n\r\n  <p><strong>Limitations:<\/strong><\/p>\r\n   <ul>\r\n \t<li>Few validation studies in total and very few subtypes of patients studied<\/li>\r\n \t<li>Has never been validated for the assessment of a suspected bleeding disorder in adults<\/li>\r\n \t<li>Requires a skilled professional to administer<\/li>\r\n<\/ul>\r\n\r\n<\/div>\r\n\r\n\r\n<div id=\"administration\" class=\"popContent\" style=\"display:none\">\r\n  <h3>Administration<\/h3>        \r\n   <ol style=\"margin-bottom:1em\">\r\n \t<li><strong>Time to complete:<\/strong> 20 minutes.<\/li>\r\n    <li><strong>Equipment\/space required:<\/strong> None.<\/li>\r\n    <li><strong>Training required:<\/strong> Expert-administered; no training specific to the administration of the scoring tool is required<\/li>\r\n    <li><strong>Cost:<\/strong> None<\/li>\r\n    <li><strong>Scoring\/scaling\/interpretation of results:<\/strong>\r\n    <ul>\r\n \t <li>Scale: 0\u20134 for each of 14 symptoms<\/li>\r\n \t <li>Possible range of total score: 0\u201356<\/li>\r\n \t <li>Differentiating features: Pediatric specific bleeding symptoms included in the \u201cother bleeding\u201d category<\/li>\r\n \t <li>Abnormal bleeding score (BS): not identified<\/li>\r\n    <\/ul>\r\n  <\/ol>\r\n\r\n<\/div>\t\r\n\r\n<div id=\"psychometrics\" class=\"popContent\" style=\"display:none\">\r\n  <h3>Psychometrics<\/h3>        \r\n  \r\n  <p><strong>Psychometric properties:<\/strong><\/p>\r\n  \r\n  <ol style=\"margin-bottom:1em\">\r\n    <li>\r\n      Construct validity:<br>\r\n      <u>Convergent validity<\/u><br>\r\n      \r\n \t  <ul>\r\n \t   <li>When comparing ISTH BAT to <a style=\"color: #e31837;\" href=\"https:\/\/elearning.wfh.org\/resource\/pediatric-bleeding-questionnaire-pbq\/\" target=\"_blank\" rel=\"noopener\">Pediatric Bleeding Questionnaire (PBQ)<\/a> in discriminating between no bleeding disorder and VWD.<sup>2<\/sup><\/li>\r\n      <\/ul>\r\n      <u>Divergent validity<\/u>\r\n      <ul>\r\n \t    <li>No difference in bleeding score (BS) between healthy controls and subjects with heritable dysfibrinogenemia (i.e. not useful in disease with mild bleeding or no bleeding phenotype).<sup>4<\/sup><\/li>\r\n      <\/ul>\r\n      <u>Group differences<\/u>\r\n      <ul>\r\n \t    <li>BSs were higher in possible platelet disorders than no bleeding disorder or mild factor deficiencies. Type 1\/2 VWD was also distinguishable from mild factor deficiencies.<sup>2<\/sup><\/li>\r\n \t    <li>BSs were higher in subjects being evaluated for possible platelet function disorder as compared to healthy controls.<sup>3<\/sup><\/li>\r\n      <\/ul>\r\n      <\/li>\r\n \t  <li>Criterion validity:\r\n \t    <ul>\r\n \t     <li>Median BS was able to distinguish between type 1 or 2 VWD versus other diagnoses.<sup>2<\/sup><\/li>\r\n        <\/ul>\r\n      <\/li>\r\n \t  <li>Reliability:\r\n \t    <ul>\r\n \t      <li>No reliability studies have been reported<\/li>\r\n        <\/ul>\r\n \t  <\/li>\r\n \t  \r\n \t<li>Responsiveness\/sensitivity:\r\n \t<ul>\r\n \t  <li>Ability to detect any mild bleeding disorder in the child when this tool was used to assess the symptoms in either the family of the child or the child being investigated (ROC-AUC of 0.764).<sup>2<\/sup><\/li>\r\n \t  <li>Inability to detect laboratory proven platelet defects (ROC AUC of 0.5).<sup>3<\/sup><\/li>\r\n    <\/ul>\r\n  <\/ol>\r\n  \r\n  <p><strong>Languages studied:<\/strong> English<sup>3,4<\/sup>, German<sup>2<\/sup><\/p>\r\n\r\n  <p><strong>Groups tested with this measure:<\/strong><\/p>\r\n  <ul style=\"margin-bottom:1em\">\r\n \t<li>Children being evaluated for suspected bleeding disorder<\/li>\r\n \t<li>Heritable dysfibrinogenemia<\/li>\r\n \t<li>Controls (\u201chealthy hospital staff\u201d)<\/li>\r\n <\/ul>\r\n\r\n  <p><strong>Age: <\/strong>Children and adults<\/p>\r\n\r\n  <p><a href=\"\/resource\/glossary-of-psychometric-properties\/\" target=\"_blank\" rel=\"noopener\"><button>Glossary of Psychometric Properties<\/button><\/a><\/p>\r\n\r\n<\/div>\r\n\r\n\r\n<div id=\"references\" class=\"popContent\" style=\"display:none\">\r\n  <h3>References<\/h3>        \r\n  <ol>\r\n   <li>Rodeghiero F et al. ISTH\/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders. <em>J Thromb Haemost<\/em> 2010; 8: 2063-2065 (plus supplementary material).<\/li>\r\n \t<li>Bidlingmaier C et al. Prospective evaluation of a pediatric bleeding questionnaire and the ISTH bleeding assessment tool in children and parents in routine clinical practice. <em>J Thromb Haemost<\/em> 2012; 10: 1335-1341.<\/li>\r\n \t<li>Lowe G et al. Utility of ISTH bleeding assessment tool in predicting platelet defects in participants with suspected platelet function disorders. <em>J Thromb Haemost<\/em> 2013 (in press).<\/li>\r\n \t<li>Shapiro SE et al. Clinical phenotype, laboratory features and genotype of 35 patients with heritable dysfibrinogenaemia. <em>Br J Haematol<\/em> 2013; 160: 220-227.<\/li>\r\n  <\/ol>\r\n\r\n<\/div>\r\n\r\n\r\n\r\n\r\n\r\n\r\n<script>\r\nfunction openTab(evt, country) {\r\n  var i, popContent, popLinks;\r\n  popContent = document.getElementsByClassName(\"popContent\");\r\n  for (i = 0; i < popContent.length; i++) {\r\n    popContent[i].style.display = \"none\";\r\n  }\r\n  popLinks = document.getElementsByClassName(\"popLinks\");\r\n  for (i = 0; i < popLinks.length; i++) {\r\n    popLinks[i].className = popLinks[i].className.replace(\" active\", \"\");\r\n  }\r\n  document.getElementById(country).style.display = \"block\";\r\n  evt.currentTarget.className += \" active\";\r\n}\r\n<\/script>\r\n   \t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1573dcd elementor-widget elementor-widget-spacer\" data-id=\"1573dcd\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t\n","protected":false},"featured_media":23133,"template":"","format":[],"old-keyword":[],"topic":[3994],"serie":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.4 - 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