{"id":32374,"date":"2026-10-23T09:00:43","date_gmt":"2026-10-23T13:00:43","guid":{"rendered":"https:\/\/elearning.wfh.org\/resource\/technologies-genetiques-pour-lhemophilie-serie-de-videos-educatives\/"},"modified":"2026-10-26T09:26:57","modified_gmt":"2026-10-26T13:26:57","slug":"technologies-genetiques-pour-lhemophilie-serie-de-videos-educatives","status":"publish","type":"resource","link":"https:\/\/elearning.wfh.org\/fr\/resource\/technologies-genetiques-pour-lhemophilie-serie-de-videos-educatives\/","title":{"rendered":"Technologies g\u00e9n\u00e9tiques pour l\u2019h\u00e9mophilie"},"content":{"rendered":"<p class=\"clamp_p\" style=\"margin-bottom: 2em;\">Explorez la science derri\u00e8re les technologies g\u00e9n\u00e9tiques pour l\u2019h\u00e9mophilie gr\u00e2ce \u00e0 cette s\u00e9rie de quatre vid\u00e9os \u00e9ducatives de la FMH. D\u00e9couvrez les notions de base sur les g\u00e8nes et l\u2019ADN, ainsi que le fonctionnement de la th\u00e9rapie g\u00e9nique par vecteur AAV, de la th\u00e9rapie g\u00e9nique lentivirale et de l\u2019\u00e9dition g\u00e9nomique. Destin\u00e9e aux personnes atteintes de troubles de la coagulation, \u00e0 leurs familles et aux professionnels de la sant\u00e9, cette s\u00e9rie offre une introduction claire et accessible \u00e0 ces approches th\u00e9rapeutiques \u00e9mergentes.<\/p>\n<div id=\"accordion\">\n<div class=\"card\" style=\"margin-bottom: .5em;\">\n<div id=\"headingOne\" class=\"card-header\">\n<h5 class=\"mb-0\">\n<div class=\"video-icon\"><i class=\"fas fa-video\"><\/i><\/div>\n<p><button class=\"btn btn-link btn-acc collapsed\" data-toggle=\"collapse\" data-target=\"#collapseOne\" aria-expanded=\"false\" aria-controls=\"collapseOne\">\u00c9pisode 1&nbsp;: Introduction<\/button><br \/>\n<\/h5>\n<\/div>\n<div id=\"collapseOne\" class=\"collapse\" aria-labelledby=\"headingOne\" data-parent=\"#accordion\">\n<div class=\"card-body\">\n<p class=\"\">Cette vid\u00e9o d\u2019introduction explique le fonctionnement des g\u00e8nes et de l\u2019ADN, ainsi que la fa\u00e7on dont les modifications g\u00e9n\u00e9tiques sont \u00e0 l\u2019origine de l\u2019h\u00e9mophilie A et B. Elle pr\u00e9sente un aper\u00e7u de trois technologies g\u00e9n\u00e9tiques actuellement \u00e0 l\u2019\u00e9tude ou utilis\u00e9es dans la prise en charge de l\u2019h\u00e9mophilie : la th\u00e9rapie g\u00e9nique par VAA, la th\u00e9rapie g\u00e9nique lentivirale et l\u2019\u00e9dition g\u00e9n\u00e9tique. Il s\u2019agit de la premi\u00e8re vid\u00e9o d\u2019une s\u00e9rie de quatre portant sur les technologies g\u00e9n\u00e9tiques pour l\u2019h\u00e9mophilie.<\/p>\n<div style=\"position: relative; width: 100%; aspect-ratio: 16 \/ 9;\"><iframe style=\"position: absolute; inset: 0; width: 100%; height: 100%; border: 1px solid #f2f4f5;\" src=\"https:\/\/www.youtube.com\/embed\/u5uVS5YP0Ro?hl=fr-CA&#038;cc_lang_pref=fr&#038;cc_load_policy=1&#038;rel=0\" loading=\"lazy\" allowfullscreen=\"allowfullscreen\"><br \/>\n<\/iframe><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"card\" style=\"margin-bottom: .5em;\">\n<div id=\"headingTwo\" class=\"card-header\">\n<h5 class=\"mb-0\">\n<div class=\"video-icon\"><i class=\"fas fa-video\"><\/i><\/div>\n<p><button class=\"btn btn-link btn-acc\" data-toggle=\"collapse\" data-target=\"#collapseTwo\" aria-expanded=\"true\" aria-controls=\"collapseTwo\">\u00c9pisode 2&nbsp;: Th\u00e9rapie g\u00e9nique par VAA<\/button><br \/>\n<\/h5>\n<\/div>\n<div id=\"collapseTwo\" class=\"collapse\" aria-labelledby=\"headingTwo\" data-parent=\"#accordion\">\n<div class=\"card-body\">\n<p class=\"\">Cette vid\u00e9o pr\u00e9sente un aper\u00e7u de la th\u00e9rapie g\u00e9nique par vecteur ad\u00e9no-associ\u00e9 (VAA) pour l\u2019h\u00e9mophilie, notamment son mode d\u2019action, les crit\u00e8res d\u2019admissibilit\u00e9, ses b\u00e9n\u00e9fices potentiels, ses limites et les consid\u00e9rations li\u00e9es au suivi. Il s\u2019agit de la deuxi\u00e8me vid\u00e9o d\u2019une s\u00e9rie de quatre portant sur les technologies g\u00e9n\u00e9tiques pour l\u2019h\u00e9mophilie.<\/p>\n<div style=\"position: relative; width: 100%; aspect-ratio: 16 \/ 9;\"><iframe style=\"position: absolute; inset: 0; width: 100%; height: 100%; border: 1px solid #f2f4f5;\" src=\"https:\/\/www.youtube.com\/embed\/aog2nYl1AeY?hl=fr-CA&#038;cc_lang_pref=fr&#038;cc_load_policy=1&#038;rel=0\" loading=\"lazy\" allowfullscreen=\"allowfullscreen\"><br \/>\n<\/iframe><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"card\" style=\"margin-bottom: .5em;\">\n<div id=\"headingThree\" class=\"card-header\">\n<h5 class=\"mb-0\">\n<div class=\"video-icon\"><i class=\"fas fa-video\"><\/i><\/div>\n<p><button class=\"btn btn-link btn-acc collapsed\" data-toggle=\"collapse\" data-target=\"#collapseThree\" aria-expanded=\"false\" aria-controls=\"collapseThree\">\u00c9pisode 3&nbsp;: Th\u00e9rapie g\u00e9nique lentivirale<\/button><br \/>\n<\/h5>\n<\/div>\n<div id=\"collapseThree\" class=\"collapse\" aria-labelledby=\"headingThree\" data-parent=\"#accordion\">\n<div class=\"card-body\">\n<p class=\"\">Cette vid\u00e9o explique la th\u00e9rapie g\u00e9nique lentivirale, une approche th\u00e9rapeutique \u00e9mergente actuellement \u00e0 l\u2019\u00e9tude pour l\u2019h\u00e9mophilie A. Elle d\u00e9crit comment cette th\u00e9rapie utilise les propres cellules souches sanguines d\u2019une personne pour introduire un g\u00e8ne fonctionnel du facteur de coagulation et favoriser une production \u00e0 long terme de ce facteur. La vid\u00e9o pr\u00e9sente \u00e9galement les b\u00e9n\u00e9fices potentiels, les consid\u00e9rations li\u00e9es \u00e0 la s\u00e9curit\u00e9 ainsi que l\u2019\u00e9tat actuel de la recherche et du d\u00e9veloppement clinique. Il s\u2019agit de la troisi\u00e8me vid\u00e9o d\u2019une s\u00e9rie de quatre portant sur les technologies g\u00e9n\u00e9tiques pour l\u2019h\u00e9mophilie.<\/p>\n<div style=\"position: relative; width: 100%; aspect-ratio: 16 \/ 9;\"><iframe style=\"position: absolute; inset: 0; width: 100%; height: 100%; border: 1px solid #f2f4f5;\" src=\"https:\/\/www.youtube.com\/embed\/BFOEelBqXCs?hl=fr-CA&#038;cc_lang_pref=fr&#038;cc_load_policy=1&#038;rel=0\" loading=\"lazy\" allowfullscreen=\"allowfullscreen\"><br \/>\n<\/iframe><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"card\" style=\"margin-bottom: .5em;\">\n<div id=\"headingFour\" class=\"card-header\">\n<h5 class=\"mb-0\">\n<div class=\"video-icon\"><i class=\"fas fa-video\"><\/i><\/div>\n<p><button class=\"btn btn-link btn-acc collapsed\" data-toggle=\"collapse\" data-target=\"#collapseFour\" aria-expanded=\"false\" aria-controls=\"collapseFour\">\u00c9pisode 4&nbsp;: \u00c9dition g\u00e9n\u00e9tique<\/button><br \/>\n<\/h5>\n<\/div>\n<div id=\"collapseFour\" class=\"collapse\" aria-labelledby=\"headingFour\" data-parent=\"#accordion\">\n<div class=\"card-body\">\n<p class=\"\">Cette vid\u00e9o pr\u00e9sente l\u2019\u00e9dition g\u00e9n\u00e9tique comme une approche th\u00e9rapeutique prometteuse \u00e0 l\u2019\u00e9tude pour l\u2019h\u00e9mophilie A et B. Elle explique comment les technologies bas\u00e9es sur CRISPR permettent de cibler l\u2019ADN avec pr\u00e9cision afin d\u2019y ins\u00e9rer des g\u00e8nes th\u00e9rapeutiques, pr\u00e9sente les diff\u00e9rentes approches d\u2019administration actuellement \u00e0 l\u2019\u00e9tude et examine les avantages potentiels ainsi que les questions qui demeurent sans r\u00e9ponse dans ce domaine en rapide \u00e9volution. Il s\u2019agit de la quatri\u00e8me vid\u00e9o d\u2019une s\u00e9rie de quatre portant sur les technologies g\u00e9n\u00e9tiques pour l\u2019h\u00e9mophilie.<\/p>\n<div style=\"position: relative; width: 100%; aspect-ratio: 16 \/ 9;\"><iframe style=\"position: absolute; inset: 0; width: 100%; height: 100%; border: 1px solid #f2f4f5;\" src=\"https:\/\/www.youtube.com\/embed\/71kOCdGwHlI?hl=fr-CA&#038;cc_lang_pref=fr&#038;cc_load_policy=1&#038;rel=0\" loading=\"lazy\" allowfullscreen=\"allowfullscreen\"><br \/>\n<\/iframe><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"alert alert-danger\" style=\"color: #333333!important; border-color: #fedede; background-color: #fdeaea; padding: 1em 1em 1em 4em; position: relative; margin-top: 1em; margin-bottom: 2em!important;\">\n<div style=\"bottom: 0; left: 0; position: absolute; top: 0; width: 4em; color: #ff7877;\">\n<p class=\"fa fa-info-circle\" style=\"left: 50%; top: 50%; position: absolute; transform: translate(-50%, -50%); font-size: 1.7em;\">\n<\/div>\n<p class=\"clamp_p\">\nLa F\u00e9d\u00e9ration mondiale de l\u2019h\u00e9mophilie ne pratique pas la m\u00e9decine et ne recommande en aucun cas de traitement pr\u00e9cis \u00e0 qui que ce soit. Pour un diagnostic ou une consultation sur un probl\u00e8me m\u00e9dical sp\u00e9cifique, la FMH vous recommande de contacter votre m\u00e9decin ou le centre de traitement local. Avant d\u2019administrer tout produit, la FMH recommande aux patients de v\u00e9rifier les doses avec un m\u00e9decin ou le personnel du centre de traitement, et de consulter les instructions \u00e9crites fournies par le laboratoire pharmaceutique.<\/p>\n<p class=\"clamp_p\">La FMH ne fait la promotion d\u2019aucun produit pharmaceutique particulier et toute mention d\u2019une marque commerciale dans cette pr\u00e9sentation est strictement \u00e0 des fins \u00e9ducatives.<\/p>\n<\/div>\n<style>#accordion {padding-bottom: 1.5rem;} #accordion .mb-0 {display: flex; gap: 4px;} .btn-acc { background:#f7f7f7!important; box-shadow: none!important;text-align:left;white-space:normal;font-size:1em} .btn-acc:focus {color: #0056b3!important;} .video-icon {width: 36px; height: 36px; border-radius: 8px; display: flex; align-items: center; justify-content: center; font-size: 16px; flex-shrink: 0; background: #e8edff; color: #3454d1; } <\/style>\n","protected":false},"featured_media":32368,"template":"","format":[3951],"old-keyword":[],"topic":[3991],"serie":[],"class_list":["post-32374","resource","type-resource","status-publish","has-post-thumbnail","hentry","topic-therapie-genique","format-videos-fr"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Technologies g\u00e9n\u00e9tiques pour l\u2019h\u00e9mophilie - eLearning Platform<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/elearning.wfh.org\/fr\/resource\/technologies-genetiques-pour-lhemophilie-serie-de-videos-educatives\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Technologies g\u00e9n\u00e9tiques pour l\u2019h\u00e9mophilie - eLearning Platform\" \/>\n<meta property=\"og:description\" content=\"Explorez la science derri\u00e8re les technologies g\u00e9n\u00e9tiques pour l\u2019h\u00e9mophilie gr\u00e2ce \u00e0 cette s\u00e9rie de quatre vid\u00e9os \u00e9ducatives de la FMH. D\u00e9couvrez les notions de base sur les g\u00e8nes et l\u2019ADN, ainsi que le fonctionnement de la th\u00e9rapie g\u00e9nique par vecteur AAV, de la th\u00e9rapie g\u00e9nique lentivirale et de l\u2019\u00e9dition g\u00e9nomique. 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